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  • Title: Preoperative exchange transfusion for sickle cell disease patients undergoing open-heart surgery: an exception to the rule.
    Author: Adhikari RK, Maddali MM, Zacharias S.
    Journal: J Card Surg; 2010 Nov; 25(6):691-3. PubMed ID: 20796092.
    Abstract:
    Preoperative exchange transfusion is a routine practice in patients with sickle cell disease having elevated sickle cell hemoglobin levels (>40%) undergoing open-heart surgery on cardiopulmonary bypass. A new approach toward acceptance and management of sickle cell disease patients with high sickle cell hemoglobin levels for open-heart surgery without preoperative exchange transfusion of blood is presented.
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