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  • Title: The influence of CS-3000 plateletapheresis on blood donors and on platelet concentrates.
    Author: Kotelba-Witkowska B, Mrowiec ZR, Daszyński J, Skrzeczkowska E, Stachecki B, Kaszkowiak M, Jakuboszczak E.
    Journal: Mater Med Pol; 1990; 22(1):29-32. PubMed ID: 2079857.
    Abstract:
    Platelet concentrates were prepared from blood of donors by means of Fenwal CS-3000, or by double centrifugation method. Platelets from CS-3000 were cryopreserved with 5% DMSO for 2-4 weeks. After thawing and washing platelets were stored in room temperature for 6 hours. Immediately after plateletapheresis the platelet count decreased by 24% and leukocyte count, Ht and Hb diminished on average 30%, 22% and 18% respectively. The efficiency of separation procedure was 45% and white cells contamination 5.8 +/-8.1 x 10(11). Significant morphological changes and the decrease in total ATP comparing to double centrifugation method were observed. Storage of platelets for 6 hours in room temperature didn't cause their quality changes. Single donor plateletapheresis method can prevent alloimmunization and diminish the risk of transmission of the viruses.
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