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  • Title: Chemical and biological sensing applications based on graphene field-effect transistors.
    Author: Ohno Y, Maehashi K, Matsumoto K.
    Journal: Biosens Bioelectron; 2010 Dec 15; 26(4):1727-30. PubMed ID: 20800470.
    Abstract:
    Chemical and biological sensors based on graphene field-effect transistors (G-FETs) were investigated. A single-layer of graphene was prepared by mechanical cleavage of natural graphite. The G-FETs were driven by a reference-gate operating in buffer solution, and exhibited very good transport characteristics. The G-FETs detected the pH value of the solution with high precision. The Dirac point shifted in the positive direction with increasing pH of the solution. The detection limit (signal/noise=3) for measuring changes in the pH of the solution was estimated to be 0.025, indicating the high sensitivity of the G-FETs. Moreover, the devices electrically detected proteins with different charge types. The drain current decreased (increased) when positively (negatively) charged proteins were added to the solution. These results indicate that the G-FETs are among the most suitable candidates for FET-based chemical and biological sensors.
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