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  • Title: Function of protein phosphatase-1, Glc7, in Saccharomyces cerevisiae.
    Author: Cannon JF.
    Journal: Adv Appl Microbiol; 2010; 73():27-59. PubMed ID: 20800758.
    Abstract:
    Budding yeast, Saccharomyces cerevisiae, and its close relatives are unique among eukaryotes in having a single gene, GLC7, encoding protein phosphatase-1 (PP1). This enzyme with a highly conserved amino acid sequence controls many processes in all eukaryotic cells. Therefore, the study of Glc7 function offers a unique opportunity to gain a comprehensive understanding of this critical regulatory enzyme. This review summarizes our current knowledge of how Glc7 function modulates processes in the cytoplasm and nucleus. Additionally, global Glc7 regulation is described.
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