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  • Title: [Use of xenogeneic spleen perfusate in the complex treatment of patients with destructive pulmonary tuberculosis].
    Author: Nikonov SD, Denisov AN, Rud' VI, Fomin IuR.
    Journal: Probl Tuberk; 1990; (10):10-2. PubMed ID: 2080151.
    Abstract:
    The first experience gained in the use of xenospleen perfusate in the management of 13 patients with disseminated fibrous-cavernous tuberculosis is presented. The disease was accompanied by an evident intoxication and respiratory insufficiency. Traditional ways of treatment failed to be effective in all the patients, thus indicating an intravenous drop by drop administration of xenogeneic spleen perfusate in the dose of 10 ml per kg body weight. The antiinflammatory (immunomodulation) effect manifested itself in the body temperature drop, less intoxication and infiltration processes in the lungs, as well as a better hemogram.
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