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  • Title: Successful treatment of superficial pyoderma gangrenosum associated with hidradenitis suppurativa with adalimumab.
    Author: Reddick CL, Singh MN, Chalmers RJ.
    Journal: Dermatol Online J; 2010 Aug 15; 16(8):15. PubMed ID: 20804692.
    Abstract:
    Pyoderma gangrenosum (PG) and hidradenitis suppurativa (HS) are chronic inflammatory dermatoses that can be a challenge to treat. A role for TNF-alpha in their pathogenesis has been postulated in the literature. A therapeutic benefit of infliximab has been reported in recalcitrant cases of both conditions. To date, there is less evidence about the use of adalimumab for these conditions. We report a patient with severe superficial PG on a background of HS, which responded to adalumimab therapy after failure of infliximab therapy.
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