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  • Title: Synthesis and antituberculosis activity of some new pyridazine derivatives. Part II.
    Author: Mantu D, Luca MC, Moldoveanu C, Zbancioc G, Mangalagiu II.
    Journal: Eur J Med Chem; 2010 Nov; 45(11):5164-8. PubMed ID: 20813433.
    Abstract:
    A series of eighteen novel compounds with pyridazine moiety were synthesized and their in vitro antituberculosis activities have been evaluated. A fast, general, and facile method for preparation of pyridazine derivatives in moderate to excellent yields is presented. Three compounds were found to be moderate active against Mycobacterium tuberculosis. Correlation of structure-biological activity has been done.
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