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  • Title: Urinary calculi associated with purine metabolism. Uric acid nephrolithiasis.
    Author: Williams-Larson AW.
    Journal: Endocrinol Metab Clin North Am; 1990 Dec; 19(4):821-38. PubMed ID: 2081513.
    Abstract:
    Uric acid stones are the consequences of abnormalities in purine metabolism, urate/uric acid renal handling, or excess dietary protein. Treatment is aimed at preventing additional formation by decreasing the degree of urate and uric acid supersaturation in urine, by altering diet, fluid intake, and the urine pH, and by blocking steps in uric acid production.
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