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  • Title: Characterization of polymorphic loci on a telomeric fragment of DNA from the long arm of human chromosome 7.
    Author: Dietz-Band J, Riethman H, Hildebrand CE, Moyzis R.
    Journal: Genomics; 1990 Sep; 8(1):168-70. PubMed ID: 2081591.
    Abstract:
    The 240-kb yeast artificial chromosome (YAC) HTY146 (D7S427) containing the telomere from the q arm of human chromosome 7 was subcloned into the cosmid vector sCOS-1. Cosmid subclones were screened for DNA polymorphisms by Southern blot analysis of restriction digests of DNA from random individuals. Four distinct polymorphisms were characterized. These markers provide a resource for defining the end of the genetic map for the long arm of human chromosome 7.
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