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  • Title: [Differences in fraction of exhaled nitric oxide values measured by two offline methods or NIOXmino in adult Japanese asthmatics].
    Author: Tsuburai T, Tsurikisawa N, Higashi N, Tatsuno S, Fukutomi Y, Tanimoto H, Sekiya K, Oshikata C, Otomo M, Maeda Y, Taniguchi M, Ikehara K, Akiyama K.
    Journal: Arerugi; 2010 Aug; 59(8):956-64. PubMed ID: 20820137.
    Abstract:
    BACKGROUND: The fraction of exhaled nitric oxide (FeNO) is a useful marker of asthma control. The FeNO measurement with two offline methods and NIOXmino may be more affordable, no studies have examined the differences in FeNO values measured with various methods in adult asthmatics. METHODS: The study population comprised 39 stable asthmatics treated with inhaled steroids at our outpatient clinic. FeNO values were measured by two offline methods (Sievers and CEIS), NIOXmino. RESULTS: FeNO(NIOXmino) values were significantly correlated with those of FeNO(Sievers) (r=0.935, P< 0.001) and FeNOCEIS (r=0.908, P< 0.001). However, FeNO(NIOXmino) values were low compared with FeNO(Sievers) (FeNO(NIOXmino)=0.848 x FeNO(Sievers)) and FeNO(CEIS) (FeNO(NIOXmino)=0.672 x FeNO(CEIS)). CONCLUSION: Differences exist in the values of FeNO measured by various methods: conversion equations are needed to compare the FeNO values among these three methods.
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