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  • Title: Computational analysis of ChIP-seq data.
    Author: Ji H.
    Journal: Methods Mol Biol; 2010; 674():143-59. PubMed ID: 20827590.
    Abstract:
    Chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq) is a new technology to map protein-DNA interactions in a genome. The genome-wide transcription factor binding site and chromatin modification data produced by ChIP-seq provide invaluable information for studying gene regulation. This chapter reviews basic characteristics of ChIP-seq data and introduces a computational procedure to identify protein-DNA interactions from ChIP-seq experiments.
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