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  • Title: Anticalculus effect of a fluoride dentifrice containing triclosan and a copolymer.
    Author: Lobene RR, Battista GW, Petrone DM, Volpe AR, Petrone ME.
    Journal: Am J Dent; 1990 Sep; 3 Spec No():S47-9. PubMed ID: 2083044.
    Abstract:
    A 3-month, double-blind, parallel and unsupervised clinical study was conducted to compare the effects on supragingival calculus formation of a dentifrice containing 0.3% triclosan and 2.0% of a copolymer, as compared to a placebo dentifrice. Subjects were initially stratified into two balanced groups based on their Volpe-Manhold Index calculus scores obtained from a 3-month pre-test period using a placebo dentifrice. All subjects received an oral prophylaxis and were assigned to the use of either a dentifrice containing 0.3% triclosan and 2.0% of a copolymer in a 0.243% sodium fluoride/silica base or a placebo dentifrice containing 0.243% sodium fluoride in a silica base. A total of 79 adult male and female subjects completed the study. The results after 3-months' use of their respective dentifrices indicated that the subjects using the triclosan/copolymer dentifrice had 26.34% less supragingival calculus formation than the subjects using the placebo dentifrice. This reduction in supragingival calculus was significant at greater than 97% level of confidence.
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