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  • Title: [A case of sigmoid colon cancer with peritoneal dissemination responding to third-line therapy employing bevacizumab combination therapy after failure of FOLFOX and FOLFIRI].
    Author: Tamura T, Ishikawa N, Koui S, Nakashima H, Minagawa N, Hachiya Y, Hirata K, Sako T, Fukuyama T, Hirano Y.
    Journal: Gan To Kagaku Ryoho; 2010 Sep; 37(9):1813-6. PubMed ID: 20841954.
    Abstract:
    A58 -year-old man with sigmoid colon cancer with peritoneal dissemination was treated with bevacizumab (BV) plus mFOLFOX6 therapy as third-line chemotherapy after treatment failures with FOLFOX4 and FOLFIRI regimen. BV combination therapy resulted in a decrease in ascites and disappearance of the primary lesion. His ECOG performance status (PS) recovered from level 3 to level 1, and BV combination therapy improved his quality of life. This case suggested that BV in combination with chemotherapy could be a promising systemic chemotherapy for patients with colorectal cancer with peritoneal dissemination, and this regimen may be useful for patients progressing after receiving FOLFOX, FOLFIRI regimen.
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