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  • Title: Giant ossifying malignant thymoma in a child.
    Author: Bikhchandani J, Valusek PA, Juang D, E O'Brien J, Hetherington M, St Peter SD.
    Journal: J Pediatr Surg; 2010 Sep; 45(9):e31-4. PubMed ID: 20850614.
    Abstract:
    We present the first reported case of an ossifying pediatric thymoma. Our patient was diagnosed with a massive thymoma replacing the whole of the left thoracic cavity. Percutaneous biopsy was attempted 3 times followed by an open incisional biopsy and adjuvant chemotherapy. Complete resection required a median sternotomy and a "trap door" thoracotomy after the tumor failed to respond to chemotherapy. Histology confirmed World Health Organization type B1 lymphocyte-rich thymoma, Masaoka stage I, with extensive osseous metaplasia.
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