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  • Title: Temporo-mesial extraventricular neurocytoma and cortical dysplasia in focal temporal lobe epilepsy.
    Author: Giulioni M, Martinoni M, Rubboli G, Marucci G, Marliani AF, Battaglia S, Badaloni F, Pozzati E, Calbucci F.
    Journal: J Clin Neurosci; 2011 Jan; 18(1):147-8. PubMed ID: 20851605.
    Abstract:
    We describe a 17-year-old boy with a left extraventricular temporo-mesial neurocytoma associated with cortical dysplasia causing focal pharmacoresistant temporal lobe epilepsy. He presented with a long history of medically refractory, temporal complex partial seizures. MRI showed a left temporo-mesial lesion suspect to be a low-grade tumor. Based on the pre-operative non-invasive neurophysiological studies, the patient underwent a left tailored temporal antero-mesial resection. Histopathological examination showed an extraventricular neurocytoma associated with architectural dysplasia (Type 1a) of the temporal pole. The patient was seizure-free at 2 years follow-up. Extraventricular neurocytomas must be considered in the differential diagnosis of the plethora of low-grade tumors associated with focal epilepsy that typically involve the temporal lobe, and are frequently associated with focal cortical dysplasia.
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