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Title: Isolation of a crotoxin-like protein from the venom of a South American rattlesnake (Crotalus durissus collilineatus). Author: Lennon BW, Kaiser II. Journal: Comp Biochem Physiol B; 1990; 97(4):695-9. PubMed ID: 2085953. Abstract: 1. A crotoxin-like protein was isolated from the venom of a South American rattlesnake Crotalus durissus collilineatus. 2. Many of its properties are similar to those of crotoxin, including its non-covalent heterodimeric structure, electrophoretic mobility on SDS-PAGE, isoelectric focusing properties, toxicity in mice, immunological reactivity, multiple isoforms, phospholipase activity, peptide map, and instability on an anion-exchange column. 3. Results indicate that "collilineatus toxin" is strongly homologous with crotoxin, found in the venom of Crotalus durissus terrificus, and all other characterized rattlesnake neurotoxins.[Abstract] [Full Text] [Related] [New Search]