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  • Title: Correction of atrophic scars with artefill: an open-label pilot study.
    Author: Epstein RE, Spencer JM.
    Journal: J Drugs Dermatol; 2010 Sep; 9(9):1062-4. PubMed ID: 20865835.
    Abstract:
    BACKGROUND: Artefill, a novel permanent filler approved by the U.S. Food and Drug Administration (FDA), has been used as an injectable implant for the correction of nasolabial folds. Fillers are considered a first line treatment for atrophic scars. OBJECTIVE: The authors evaluated the degree of correction and subject satisfaction of correction of atrophic acne scar(s) after injection of Artefill. METHODS: Fourteen qualified subjects participated in a single-center, open-label, pilot study. Atrophic acne scars were evaluated prior to injection. Subscision was performed, and then Artefill was injected into the scar. The degree of improvement was measured at weeks 2 and 4 and month 8. Subjects were asked to fill out a satisfaction survey at their eight-month visit. RESULTS: Investigator ratings after eight months post procedure indicated that 96 percent of the atrophic acne scars showed some degree of improvement. There was no improvement in two out of a total of 57 scars evaluated. The majority of patients reported a moderate correction, correlating with a 51-75 percent improvement in their acne scars at eight months. No adverse events or side effects were noted. CONCLUSION: Artefill demonstrated to be both an efficacious and safe therapy for the treatment of atrophic acne scars.
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