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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: Studies on polypeptide receptors a critical view on the mechanism of ACTH action.
    Author: Schwyzer R.
    Journal: Bull Schweiz Akad Med Wiss; 1978 Mar; 34(1-3):263-74. PubMed ID: 208696.
    Abstract:
    Recent work on ACTH receptors in adrenal cells and adipocytes is reviewed. It is suggested that ACTH acts on two types of receptor: an adenylate cyclase receptor and another one that helps to guide cAMP into the correct compartment. The introduction of the term holoreceptor to indicate a unit that is recognized by the hormone and is able to produce a measurable effect, and of the terms discriminator, transmitter and effector to indicate the functional subunits of the holoreceptor is suggested as a measure enhancing clarity and flexibility of communication in this very complex field.
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