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  • Title: Congenital syphilis in Italy: a multicentre study.
    Author: Tridapalli E, Capretti MG, Reggiani ML, Stronati M, Faldella G, Italian Neonatal Task Force of Congenital Syphilis for The Italian Society of Neonatology – Collaborative Group.
    Journal: Arch Dis Child Fetal Neonatal Ed; 2012 May; 97(3):F211-3. PubMed ID: 20870907.
    Abstract:
    OBJECTIVE: To study the prevalence of congenital syphilis and its risk factors in Italy. STUDY DESIGN: Prospective study from 1 July 2006 to 30 June 2007. Data on mother-child pairs were collected for every syphilis seropositive mother. RESULTS: Maternal syphilis seroprevalence at delivery was 0.17%. 207 infants were born to 203 syphilis seropositive mothers. In 25 newborns it was possible to diagnose congenital syphilis (20/100,000 live births). Maternal risk factors included age <20 years, no antenatal care and no adequate treatment. The infected babies were more often preterm or weighed <2000 g at birth. DISCUSSION: Many syphilis seropositive mothers were foreign born but the risk of an infected newborn was not higher in foreign-born than in Italian seropositive women. The significant factors were lack of antenatal screening and inadequate maternal treatment. CONCLUSION: Syphilis is a re-emerging infection in Italy. Prevention strategies should include antenatal serological tests for all pregnant women and treatment for infected mothers.
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