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  • Title: Synchronous choroid plexus papilloma of the fourth ventricle and ependymoma of the filum terminale: case report.
    Author: Bollo RJ, Zagzag D, Samadani U.
    Journal: Neurosurgery; 2010 Nov; 67(5):E1454-9; discussion E1459. PubMed ID: 20871433.
    Abstract:
    BACKGROUND AND IMPORTANCE: We report the first case of synchronous choroid plexus papilloma of the fourth ventricle and myxopapillary ependymoma of the filum terminale. Both are papillary World Health Organization grade I tumors known to disseminate via cerebrospinal fluid pathways. CLINICAL PRESENTATION: A 65-year-old man presented with an incidental mass in the fourth ventricle found on a computed tomography scan of the head after a motor vehicle collision and an intradural mass of the filum terminale. The patient underwent resection of the fourth ventricle mass. After pathological diagnosis of a choroid plexus papilloma, the patient underwent resection of the spinal cord tumor. CONCLUSION: This case underscores the need for separate pathological diagnosis in a patient with an intradural spine lesion in the context of a benign intracranial lesion. We detail a panel of immunohistochemical markers essential for distinguishing the 2 papillary neuroectodermal tumors recovered in this case.
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