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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: Interference of circulating endogenous antibodies on the Dimension® DGNA digoxin immunoassay: elimination with a heterophilic blocking reagent.
    Author: Hermida-Cadahía EF, Calvo MM, Tutor JC.
    Journal: Clin Biochem; 2010 Dec; 43(18):1475-7. PubMed ID: 20875811.
    Abstract:
    Only two cases have been previously described about circulating endogenous antibodies interference on the immunochemical determination of digoxin. In an elderly patient with history of social cat handling was observed a moderate positive interference (about 0.8 ng/mL) on the Dimension® DGNA digoxin immunoassay (capture rabbit antibody), which was eliminated treating the serum samples with a heterophilic blocking reagent. The Architect® immunoassay was not affected.
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