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  • Title: Carrier mediated protein and peptide stabilization.
    Author: Tiwari AK, Gajbhiye V, Sharma R, Jain NK.
    Journal: Drug Deliv; 2010 Nov; 17(8):605-16. PubMed ID: 20879837.
    Abstract:
    Proteins and peptides are complex macromolecules that are prone to change in their native structure during storage, which causes undesired side-effects after their administration. During past decades, bioactive carriers have played an important role in stabilization of proteins. Incorporation of the protein and peptides into a particulate carrier can protect it against degradation in vitro and in vivo, the release can be controlled,and it also offers possibilities for targeting. This review has focused on a wide range of bioactive carriers used in protein stabilization during long time storage. Bioactive carriers can protect the bioactives from degradation, resulting in increased bioavailability of protein.
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