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  • Title: [Effect of buprenorphine on external pancreatic secretion in rats].
    Author: Nagain C, Chariot J, Roze C, Vaille C.
    Journal: Ann Pharm Fr; 1990; 48(5):248-54. PubMed ID: 2088160.
    Abstract:
    2-deoxyglucose stimulates pancreatic secretion through a mainly vagal neural pathway. Buprenorphine antagonized this stimulation in a dose-related fashion between 0.017 and 0.45 mg/kg. i.v. The effect of buprenorphine was suppressed by naloxone, but not by alpha and beta-adrenoceptor blocking agents. The effect of methadone was similar, at doses about ten times larger.
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