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  • Title: Eruptive microvenular hemangiomas in 4 Chinese patients: clinicopathologic correlation and review of the literature.
    Author: Xu XL, Xu CR, Chen H, Cao YH, Zeng XS, Sun JF, Guo Y.
    Journal: Am J Dermatopathol; 2010 Dec; 32(8):837-40. PubMed ID: 20881833.
    Abstract:
    Microvenular hemangioma (MVH) is an uncommon benign vascular neoplasm that usually occurs as a solitary asymptomatic red or purple papule, nodule, or plaque with a predilection for the upper extremities. Patients with more than 1 lesion, that is, multiple MVHs, are extremely rare. We describe the clinicopathologic features of 4 Chinese patients who had a rapidly progressive abrupt onset of numerous MVHs numbering in the tens to hundreds. Clinically, the correct diagnosis of MVH could not be made in any of our patients; however, histologic examination revealed the characteristic features of MVH. Immunohistochemical stains were performed in all cases and showed the vessel lining cells to be positive for CD34, CD31, and factor VIII-related antigen. Polymerase chain reaction for human herpesvirus-8 was negative in all cases. The differential diagnosis and review of the literature of patients with multiple MVHs are presented.
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