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  • Title: Disseminated intravascular coagulation with intracranial haematoma in neonatal congenital syphilis.
    Author: Grover SB, Mahato S, Chellani H, Saluja S, Rajalakshmi GP.
    Journal: J Trop Pediatr; 2011 Aug; 57(4):315-8. PubMed ID: 20889622.
    Abstract:
    Disseminated intravascular coagulation (DIC) although a well known complication in neonatal sepsis is extremely rare in congenital syphilis and there are scanty reports of this entity in the literature. Intracranial bleeding following DIC in neonatal congenital syphilis is even rarer, and has been reported only once earlier. We are reporting the second case of neonatal DIC with intracranial haematoma due to congenital syphilis in a newborn. Our patient also had clinical and biochemical evidence of hepatitis which predisposes to DIC. Extensive investigations and emergent use of imaging modalities including ultrasound and CT scan led to early diagnosis and treatment in our patient, who could therefore be salvaged from an otherwise life threatening disease.
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