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  • Title: β(1,3) Branched heptadeca- and linear hexadeca-saccharides possessing an aminoalkyl group as a strong ligand to dectin-1.
    Author: Tanaka H, Kawai T, Adachi Y, Ohno N, Takahashi T.
    Journal: Chem Commun (Camb); 2010 Nov 21; 46(43):8249-51. PubMed ID: 20890487.
    Abstract:
    In this report, we describe the convergent synthesis of β(1,3) oligosaccharides containing an aminoalkyl group. The branched heptadecasaccharide and linear hexadecasaccharide acted as ligands of dectin-1 whose binding affinity was only 10-fold weaker than that of natural SPG and exhibited dectin-1 agonist activity.
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