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  • Title: [Status of cell surface of hepatocytes after exposure to carbon tetrachloride].
    Author: Ushakov VF, Palienko LA, Livshits KI, Grisha NP, Kramar' SD, Filimonova LA.
    Journal: Arkh Anat Gistol Embriol; 1990 Dec; 99(12):44-8. PubMed ID: 2090059.
    Abstract:
    In order to estimate contact interactions and deformity of the surface of hepatocytes at a toxic hepatitis, produced by means of carbon tetrachloride, a morphometric analysis of ultrastructures of the contacts and retractions of the surface of hepatocytes, formed at an increased intraorganic pressure has been performed. Carbon tetrachloride produces decrease in adhesive interactions of the cellular surfaces in the area of simple connections, decrease in amount of desmosomes and results in increasing deformity of the surface of hepatocytes. These data support that there exists a universal reaction of the intercellular contacts to a damaging action.
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