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  • Title: [Hemorheological properties of new xanthine derivative studied on model of streptozotocin induced diabetes mellitus].
    Author: Naumenko LV, Kuznetsova VA, Spasov AA, Murav'ev AV, Khaliullin FA.
    Journal: Eksp Klin Farmakol; 2010 Aug; 73(8):29-31. PubMed ID: 20919555.
    Abstract:
    Influence of a new xanthine derivative SUM-55 on microrheological properties erythrocytes in rats with experimental diabetes has been investigated. It is shown that compound SUM-55 significantly reduces aggregation and increases deformability of erythrocytes. Comparative analysis showed that SUM-55 is comparable with pentoxyphylline in the ability to reduce aggregation of erythrocytes and is superior to the reference drug in increasing deformability of red bloodcells.
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