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  • Title: The epidemiology of ocular and nasal allergy in the United States, 1988-1994.
    Author: Singh K, Axelrod S, Bielory L.
    Journal: J Allergy Clin Immunol; 2010 Oct; 126(4):778-783.e6. PubMed ID: 20920769.
    Abstract:
    BACKGROUND: Allergies give rise to the fifth-leading group of chronic diseases. However, the specific prevalence of ocular allergy is poorly described. OBJECTIVE: We sought to provide a more accurate representation of the epidemiology of ocular allergy in the United States. METHODS: The National Health And Nutrition Examination Survey III performed in the United States from 1988-1994 was the source for the data collected. Items from the questionnaire regarding ocular and nasal allergy symptoms in relation to skin prick testing were stratified by age, race, region, and sex. RESULTS: The sample size is 20,010: 1,285 (6.4%) reported ocular symptoms, 3,294 (16.5%) reported nasal symptoms, 5,944 (29.7%) reported both ocular and nasal symptoms, and 9.487 (47.4%) were asymptomatic. Forty percent of the population reported at least 1 occurrence of ocular symptoms in the past 12 months. Those 50 years and older have a higher frequency of isolated ocular symptoms (P < .001). There is an increase in the frequency of symptoms in those younger than 50 years in the populations of subjects with ocular and nasal symptoms combined and isolated nasal symptoms (P < .001). Ocular symptoms are more frequent than nasal symptoms in relation to animals (P < .001), household dust (P < .001), and pollen (P < .001). CONCLUSION: This analysis provides the first representation of the epidemiology of ocular allergy in the United States. Up to 40% of the population, the highest reported to date, have experienced ocular symptoms at least once in their lifetime, with a peak of symptoms in the months of June and July.
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