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  • Title: New antitumor principles, casearins A-F, for Casearia sylvestris Sw. (Flacourtiaceae).
    Author: Itokawa H, Totsuka N, Morita H, Takeya K, Iitaka Y, Schenkel EP, Motidome M.
    Journal: Chem Pharm Bull (Tokyo); 1990 Dec; 38(12):3384-8. PubMed ID: 2092935.
    Abstract:
    New antitumor clerodane diterpenes, named casearins A-F, have been isolated from the leaves of Casearia sylvestris Sw. (Flacourtiaceae). These structures have been completely elucidated by two dimensional nuclear magnetic resonance, circular dichroism spectroscopy, X-ray analysis, and chemical evidences.
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