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  • Title: Glucose-responsive insulinoma in a patient with postprandial hypoglycemia in the morning.
    Author: Iida K, Ohara T, Hino Y, Nobuhara M, Ishida J, Chihara K.
    Journal: Intern Med; 2010; 49(19):2123-7. PubMed ID: 20930440.
    Abstract:
    We report the case of an obese 79-year-old woman who experienced postprandial hypoglycemia in the morning. The serum immunoreactive insulin (IRI) and C-peptide levels responded in parallel with her serum glucose level during a 75-g oral glucose tolerance test. A prolonged fast test lowered her serum glucose level to 30 mg/dL, but serum IRI was not fully suppressed. Abdominal computed tomography revealed a tumor in the uncinate process of the pancreas. The tumor was histologically diagnosed as benign insulinoma after surgery. Therefore, glucose-responsive insulinoma as well as reactive hypoglycemia should be considered in patients who exhibit postprandial hypoglycemia.
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