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  • Title: [Double-blind controlled comparison of placebo and paracetamol in patients with G-6-PD deficiency].
    Author: Cottafava F, Nieri S, Franzone G, Sanguinetti M, Bertolazzi L, Ravera G.
    Journal: Pediatr Med Chir; 1990; 12(6):631-7. PubMed ID: 2093885.
    Abstract:
    In this study are reported 17 patients with G-6-PD deficiency. These subjects have been studied with double-blind trial between placebo and Paracetamol, looking for the possible hemolysis induced from drug in these children with G-6-PD deficiency. Hemolysis had been valued by various hematological parameters (Hb, erythrocyte count, reticulocytosis, bilirubinemia, haptoglobin, hemopexin, and survival of erythrocytes marked with Cr). The results (8 cases with placebo and 9 cases with paracetamol) demonstrate that paracetamol have not induced hemolysis in these G-6-PD deficient subjects.
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