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  • Title: New anti-HBV caryophyllane-type sesquiterpenoids from Euphorbia humifusa Willd.
    Author: Tian Y, Sun LM, Li B, Liu XQ, Dong JX.
    Journal: Fitoterapia; 2011 Mar; 82(2):251-4. PubMed ID: 20940034.
    Abstract:
    Activity-guided fractionation of Euphorbia humifusa for anti-HBV activity led to the isolation of two novel sesquiterpenoids, named humifusane A (1) and humifusane B (2). Their structures were elucidated by spectral data to show that they have a caryophyllane-type precursor structure. The two new sesquiterpenoids showed anti-HBV activities through specifically inhibiting the secretion of HBsAg in HepG2.2.15.
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