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Title: [Process of organ donation at a maximum care hospital]. Author: Kaiser GM, Heuer M, Stanjek M, Schoch B, Müller O, Waydhas C, Mummel P, Radunz S, Wirges U, Lütkes P, Philipp T, Schmid KW, Paul A. Journal: Dtsch Med Wochenschr; 2010 Oct; 135(42):2065-70. PubMed ID: 20941679. Abstract: BACKGROUND: A chronic shortage of organs for transplantation has developed due to the disparity between the demand for solid organs and the current supply. Improved processes for identifying potential donors could expand the pool of available organs. PATIENTS AND METHODS: All patients who died between January 1, 2006 and December 31, 2008 in the University hospital of Essen suffering from a primary or secondary cerebral injury were assessed retrospectively. Age, date of death, duration of stay in the intensive care unit, main and additional diagnoses and diagnostic test for assessing brain death as well as discussions with relatives were recorded anonymously. RESULTS: 424 deaths with primary or secondary cerebral injury (group A) were identified during the study period. 267 deaths (62.9 %) (group B) were further evaluated for organ donation after excluding absolute medical contraindications, e. g. malignancies, multiple organ failure. In 68 cases (16.0 %), diagnostic test of brain death had been completed (group C). Despite a high refusal rate, 36 (8.5 %) organ procurements were realized (group D) resulting in 140 transplanted organs (3.9 per organ donor). CONCLUSION: The first crucial step to improve the rate of organ donation is to identify any potential donor. In 8.5 % of intensive care unit deaths with primary or secondary cerebral damage, organ procurement was realized. In addition, education regarding transplant medicine and a positive attitude to organ donation among the general public as well as medical personnel is necessary to minimize the high refusal rates.[Abstract] [Full Text] [Related] [New Search]