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  • Title: Four diphenylpropanes and a cycloheptadibenzofuran from Bussea sakalava from the Madagascar dry forest.
    Author: Pan E, Harinantenaina L, Brodie PJ, Miller JS, Callmander MW, Rakotonandrasana S, Rakotobe E, Rasamison VE, Kingston DG.
    Journal: J Nat Prod; 2010 Nov 29; 73(11):1792-5. PubMed ID: 20942441.
    Abstract:
    Investigation of the endemic Malagasy plant Bussea sakalava for antiproliferative activity against the A2780 ovarian cancer cell line led to the isolation of the four new diphenylpropanes 1-4 and the new cycloheptadibenzofuran 5; compound 5 has a previously unreported natural product skeleton. The structure elucidation of these compounds was based on the analysis of their 1D and 2D NMR and mass spectroscopic data. Compounds 1-5 were tested for antiproliferative activity against the A2780 human ovarian cancer cell line.
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