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  • Title: Label-free biosensing based on single gold nanostars as plasmonic transducers.
    Author: Dondapati SK, Sau TK, Hrelescu C, Klar TA, Stefani FD, Feldmann J.
    Journal: ACS Nano; 2010 Nov 23; 4(11):6318-22. PubMed ID: 20942444.
    Abstract:
    Gold nanostars provide high sensitivity for single nanoparticle label-free biosensing. The nanostars present multiple plasmon resonances of which the lower energy ones, corresponding to the nanostar tips and core-tip interactions, are the most sensitive to environmental changes. Streptavidin molecules are detected upon binding to individual, biotin-modified gold nanostars by spectral shifts in the plasmon resonances. Concentrations as low as 0.1 nM produce a shift of the tip related plasmon resonances of about 2.3 nm (5.3 meV).
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