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  • Title: Acute kidney injury requiring dialysis secondary to adenovirus nephritis in renal transplant recipient.
    Author: Sujeet K, Vasudev B, Desai P, Bellizzi J, Novoa-Takara L, He C, El-Meanawy A.
    Journal: Transpl Infect Dis; 2011 Apr; 13(2):174-7. PubMed ID: 20946204.
    Abstract:
    Disseminated adenoviral infection is a serious problem, especially in an immunocompromised host. The disease carries a mortality rate reaching as high as 80%. It is seen most frequently in bone marrow transplant recipients, where it causes pneumonia and disseminated disease. In solid organ transplant recipients it causes graft infection. We report the case of a renal transplant recipient with disseminated adenoviral infection and acute kidney failure requiring dialysis. Reduction of immunosuppression and 1 dose of cidofovir were associated with resolution of viremia and viruria and return of kidney function to near baseline.
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