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  • Title: [Vitamin D revisited: a cornerstone of health?].
    Author: Bacchetta J, Ranchin B, Dubourg L, Cochat P.
    Journal: Arch Pediatr; 2010 Dec; 17(12):1687-95. PubMed ID: 20951011.
    Abstract:
    There is a recent renewed interest in vitamin D metabolism and pathophysiology, due to its recent description as a hormone with a positive impact on global health rather than a strictly bone hormone: vitamin D could be a protective factor against infection, autoimmunity, cardiovascular morbidity, and cancer. By contrast, vitamin D deficiency appears to be increasingly frequent worldwide. We propose a review of these new aspects of vitamin D metabolism, with a focus on vitamin D status in a local pediatric cohort. There is an urgent need for revisiting current guidelines on vitamin D supplementation and for closely monitoring serum vitamin D in children with chronic diseases, i.e., at greater risk of cardiovascular impairment, bone morbidity, infectious disease, and acute inflammation.
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