These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Osteopontin expression in salivary gland carcinomas.
    Author: Bjørndal K, Larsen SR, Godballe C, Krogdahl A.
    Journal: J Oral Pathol Med; 2011 Jul; 40(6):451-5. PubMed ID: 20969634.
    Abstract:
    BACKGROUND: In several cancer types, osteopontin (OPN) expression has been correlated with tumor progression and prognosis. Two earlier studies have examined OPN expression in salivary gland carcinomas with contradictory results. METHODS: One hundred and seventy-five patients with a primary salivary gland carcinoma diagnosed from January 1, 1990 to December 31, 2005 were identified in the local pathology register, Odense University Hospital. Criteria as documented by Allred et al. were used to assess OPN immunostaining that was performed on surgical specimens. RESULTS: Osteopontin was expressed in all salivary gland carcinomas. Adenoid cystic carcinomas had the highest mean sum score (7.3) and a significantly higher proportion of carcinomas with high OPN sum score than both mucoepidermoid carcinoma and acinic cell carcinoma. Correlation of OPN expression with known prognostic factors in salivary gland carcinomas was insignificant. CONCLUSIONS: Salivary gland carcinomas express OPN. The expression does not correlate with known prognostic factors.
    [Abstract] [Full Text] [Related] [New Search]