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Title: [Clinical endocrine investigations in patients with pituitary adenoma (author's transl)]. Author: Mühlenstedt D, Hanker J, Schneider HP. Journal: Arch Gynakol; 1978 Jul 19; 225(3):237-45. PubMed ID: 209760. Abstract: LH-RH tests of hypothalamo-pituitary gonadotropinfunction were performed in 26 patients with pituitary adenomata before and after prolactin suppression and/or surgical treatment. Various degrees of galactorrhea together with menstrual disorders were the key symptoms in all patients. There was a significant association of elevated prolactin levels with impaired LH-responses. Seven patients have undergone transspenoidal dissection of the pituitary adenoma and in five of them the pituitary LH-response reverted to normal (R2) after surgery. Nine of 15 amenorrhoic patients had a recurrence of menstrual cyclicity, partly biphasic within 3 months and a normalized LH-response after Bromocriptin therapy. 19 of our patients were desirous of pregnancy. Five pregnancies were confirmed within 4 months of treatment.[Abstract] [Full Text] [Related] [New Search]