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  • Title: Histone H1 and the regulation of transcription of eukaryotic genes.
    Author: Zlatanova J.
    Journal: Trends Biochem Sci; 1990 Jul; 15(7):273-6. PubMed ID: 2098005.
    Abstract:
    Histone H1 plays a role in the formation of chromatin structure, both at the level of the nucleosome particle itself and in the formation of the higher-order structures of the chromatin fibre. Histone H1 is regarded as a part of a general repressor mechanism that ensures a strong and stable repression of gene expression. In addition to serving as a general repressor for relatively large chromatin fragments, histone H1 might also be involved in controlling the transcriptional activity of individual genes.
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