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  • Title: [Pneumocystis carinii pneumonia in patients with HIV infection at a Spanish hospital].
    Author: Fortún J, Hermida JM, Hernández-Cabrero J, Martí-Belda P, Sueiro A, Fogué L, Sanz I, Buzón L.
    Journal: Enferm Infecc Microbiol Clin; 1990 Feb; 8(2):82-7. PubMed ID: 2098145.
    Abstract:
    Thirty cases of a first episode of Pneumocystis carinii pneumonia in patients with HIV infection were collected in a 32 month period. Most patients had long standing fever, cough and dyspnea. Laboratory findings were nonspecific. Remarkably, LDH activity was high in 88% of patients and the T4 lymphocyte count was lower than 200/mm3 in all patients in whom it was measured. Chest radiogram showed bilateral alveolar-interstitial pattern in 90% of cases. Bronchoalveolar lavage with ultracentrifugation was found to be the most effective diagnostic study, with 95% sensitivity. The frequency of secondary effects to cotrimoxazole which required to change to pentamidine was 13.3%. During hospital admission, 16.6% of the patients died, and the survivors had mortality rates of 4% and 85% after 3 and 20 months, respectively.
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