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  • Title: Effect of chronic clonidine treatment on urinary growth hormone excretion and linear growth in children with short stature.
    Author: Sanmartí A, Lucas A, Granada ML, Salinas I, Reverter JL, Cuatrecasas JM, Foz M, Audi L.
    Journal: Horm Res; 1990; 34(5-6):193-6. PubMed ID: 2100275.
    Abstract:
    Eleven prepubertal children with short stature were treated with clonidine (0.15 mg/m2 daily) for a period of 1 year. The effect of this drug was evaluated on both clinical (growth velocity, height standard deviation scores for chronological age and bone age) and hormonal (urinary growth hormone excretion and insulin-like growth factor I) parameters. Our study shows that long-term clonidine administration in children with short stature did not result in significant differences in growth velocity, height standard deviation scores for chronological age and bone age, insulin-like growth factor I or in urinary growth hormone excretion.
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