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  • Title: Protective action of coenzyme A on paracetamol-induced tissue depletion of glutathione.
    Author: Bertelli A, Bertelli AA, Giovannini L, Mian M, Spaggiari P.
    Journal: Int J Tissue React; 1990; 12(6):353-8. PubMed ID: 2102899.
    Abstract:
    Paracetamol toxicity induced in mice a significant depletion in hepatic and renal glutathione concentrations. The administration of CoA in animals prevents the mortality induced by paracetamol and simultaneously prevents the reduction in renal and hepatic glutathione concentrations.
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