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  • Title: Living-unrelated renal transplantation at the University of Wisconsin.
    Author: Pirsch JD, D'Alessandro AM, Sollinger HW, Voss BJ, Knechtle SJ, Reed A, Kalayoglu M, Belzer FO.
    Journal: Clin Transpl; 1990; ():241-5. PubMed ID: 2103149.
    Abstract:
    1. Use of LUrDs under a DST protocol results in a 70% actuarial graft survival at 6 years which is not statistically different from haploidentical or primary cadaver recipients transplanted over the same time period. 2. Sensitization is common, despite the use of Aza, especially in husband-to-wife donor-to-recipient relationship. 3. Rejection occurs frequently, despite the use of DST, however, it is usually reversible. The high rejection rate did not influence the quality of long-term graft survival with very few patients losing grafts to chronic rejection. 4. Expansion of the use of LUrDs could help provide additional organs for transplantation.
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