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  • Title: Cellular and viral ligands that interact with the EGF receptor.
    Author: Todaro GJ, Rose TM, Spooner CE, Shoyab M, Plowman GD.
    Journal: Semin Cancer Biol; 1990 Aug; 1(4):257-63. PubMed ID: 2103500.
    Abstract:
    The growth regulatory functions of a family of structurally related polypeptides are mediated through the membrane-bound epidermal growth factor receptor molecule. This ligand family includes epidermal growth factor, transforming growth factor-alpha, amphiregulin, and polypeptides encoded by several poxviruses. The structural and functional properties that are characteristic of the ligand family provide a basis for possible evolutionary relationships among the various ligands.
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