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  • Title: The predictive value of suspicious sonographic characteristics in atypical cyst-like breast lesions.
    Author: Tea MK, Grimm C, Heinz-Peer G, Delancey J, Singer C.
    Journal: Breast; 2011 Apr; 20(2):165-9. PubMed ID: 21035340.
    Abstract:
    BACKGROUND AND PURPOSE: Simple breast cysts are a common sonographic finding and do not require further diagnostic evaluation. In contrast, atypical breast cysts do harbour a risk of malignancy. The purpose of this study was to evaluate the predictive value of sonographic findings that are considered characteristic of malignant atypical cyst-like lesions. PATIENTS AND METHODS: Six descriptive sonographic criteria of 202 atypical cysts in 176 women were compared with histopathological findings after surgical excision and their statistical association was evaluated. RESULTS: Of these six criteria thick cyst wall (p < 0.0001), lobulation (p = 0.0001) and hyperechogenicity (p = 0.003) were found to be highly predictive of breast cancer. The presence of two or more sonographic criteria was associated with a 10.3 times greater risk of malignancy (p < 0.0001). CONCLUSION: The association between suspicious sonographic criteria and histology after surgery was evaluated. We propose surgical excision when two or more sonographic criteria are diagnosed in a single atypical breast cyst.
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