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  • Title: Presurgical language fMRI activation correlates with postsurgical verbal memory decline in left-sided temporal lobe epilepsy.
    Author: Labudda K, Mertens M, Aengenendt J, Ebner A, Woermann FG.
    Journal: Epilepsy Res; 2010 Dec; 92(2-3):258-61. PubMed ID: 21036014.
    Abstract:
    We analysed the association of presurgical language fMRI activations and postsurgical verbal memory changes in 16 left-sided mesial temporal lobe epilepsy patients with initially intact memory. Patients with severe verbal memory decline after surgery (n = 9) had stronger presurgical fMRI activations within the left posterior temporal lobe, compared to those with no decline (n = 7). Language fMRI activation may predict verbal memory outcome, even in patients with a high risk of postsurgical memory deterioration.
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