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  • Title: Less invasive versus conventional double-valve surgery: a propensity-matched comparison.
    Author: Atik FA, Svensson LG, Blackstone EH, Gillinov AM, Rajeswaran J, Lytle BW.
    Journal: J Thorac Cardiovasc Surg; 2011 Jun; 141(6):1461-8.e4. PubMed ID: 21036369.
    Abstract:
    OBJECTIVE: Less invasive approaches to double-valve surgery are used for improved cosmesis; however, few studies have investigated their effect on outcome. We sought to compare these less invasive approaches with conventional full sternotomy. METHODS: From January 1995 to January 2004, 114 patients underwent primary double-valve surgery through a less invasive approach and 381 through conventional sternotomy. Because there were important differences in the patients' characteristics, a propensity score based on 42 factors was used to obtain 81 well-matched patient pairs (71% of possible matches) for comparison of in-hospital morbidity and mortality, mediastinal drainage, transfusion requirements, pulmonary function, pain, and long-term survival. RESULTS: In-hospital mortality was similar for propensity-matched patients: 6.2% (5/81) for those undergoing less invasive surgery and 2.5% (2/81) for those undergoing conventional sternotomy (P > .4). Occurrences of stroke (P > .9), renal failure (P = .4), myocardial infarction (P > .9), and infection (P > .9) were also similar. However, 24-hour mediastinal drainage was less after less invasive surgery (median, 250 vs 400 mL; P < .0001), but a similar proportion of patients received transfusions (28% vs 40%, P = .2). An equivalent proportion of patients were extubated in the operating room (7.7% vs 7.0%, P > .9), and median hours to extubation were similar (5.0 vs 6.5 hours). Pain scores were equivalent (P > .3). Long-term survival was also similar (82% and 76% at 10 years, P = .07). CONCLUSIONS: Within that portion of the spectrum of double-valve surgery in which propensity matching was possible, less invasive surgery had cosmetic and blood product use advantages over conventional surgery and no apparent detriments.
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