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  • Title: dnaX36 Mutator of Escherichia coli: effects of the {tau} subunit of the DNA polymerase III holoenzyme on chromosomal DNA replication fidelity.
    Author: Gawel D, Jonczyk P, Fijalkowska IJ, Schaaper RM.
    Journal: J Bacteriol; 2011 Jan; 193(1):296-300. PubMed ID: 21036999.
    Abstract:
    The Escherichia coli dnaX36 mutant displays a mutator effect, reflecting a fidelity function of the dnaX-encoded τ subunit of the DNA polymerase III (Pol III) holoenzyme. We have shown that this fidelity function (i) applies to both leading- and lagging-strand synthesis, (ii) is independent of Pol IV, and (iii) is limited by Pol II.
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